Jan 15, 2017 (San Diego) Once again the San Diego port of entry on the Mexican side was taken by protesters. The US side was closed by authorities, and if you want to go to Mexico take the Otay Mesa crossing.
This is the Caltrans tweet
SB I-5 and SB I-805 are closed at the US/MX Border. Traffic being diverted at SR-905. Use Otay Mesa Port of Entry.